Name: Dr. Ilyse S. Lefkowicz,
Specialty: Dermatology | General Dermatology
Qualification/Board Certification: George Washington University School of Medicine Affiliation(s): Mount Sinai Hospital | Debra J. Wattenberg, M.D., P.C.
Location (City/State): New York, New York
Spoken: English
Accepting New Patients: Yes
NPI Number: 1164432043
About the Doctor
Dr. Ilyse S. Lefkowicz is a distinguished and deeply patient-centered dermatologist whose elite medical education, strong academic training, prestigious hospital affiliation, and exceptional patient satisfaction record have established her as one of New York City’s most trusted and highly recommended skin care specialists. She earned her medical degree from George Washington University School of Medicine — one of the nation’s respected private medical schools with a strong tradition of training compassionate, clinically excellent physicians — and completed her internal medicine internship at Westchester Medical Center from 1998 to 1999. She subsequently completed her dermatology residency at Rutgers Health/Robert Wood Johnson Medical School from 2002 to 2005 — a respected academic dermatology program affiliated with one of New Jersey’s premier medical schools — emerging with comprehensive training across the full breadth of medical and procedural dermatology.
Dr. Lefkowicz practices at Debra J. Wattenberg, M.D., P.C. — a distinguished dermatology practice located on the Upper East Side of Manhattan at 875 Fifth Avenue — serving patients in one of New York City’s most prestigious residential and medical communities. Her practice within this well-regarded dermatology office provides patients with access to personalized, high-quality skin care in a boutique, patient-focused practice setting that prioritizes individual attention and thorough clinical evaluation.
Her hospital affiliation with Mount Sinai Hospital is a mark of exceptional professional distinction. Mount Sinai Hospital is a Best Hospitals Honor Roll institution and the #1-ranked hospital in New York — one of the most competitive and demanding designations available in American medicine. This affiliation places Dr. Lefkowicz within a world-class academic medical ecosystem that is continuously driving the frontiers of dermatological research, treatment innovation, and clinical excellence.
Her patient satisfaction record is equally impressive. With a perfect 5 out of 5 overall rating based on 14 total reviews — and perfect scores for her ability to answer questions and clarity of instructions — Dr. Lefkowicz has earned five distinguished patient experience awards: Patients’ Top Choice, Patients Recommend, Makes Time for Patients, Listens Attentively, and Clearly Explains. These awards reflect a physician who brings genuine attention, patience, and communicative excellence to every patient encounter — qualities that are especially valued in dermatology, where patients often arrive with long-standing skin concerns, diagnostic uncertainty, or anxiety about potential malignancies that require both clinical expertise and compassionate reassurance. She holds an active New York State Medical License through 2027.
Education & Training
Medical School – George Washington University School of Medicine (MD)
Internship – Internal Medicine, Westchester Medical Center (1998–1999)
Residency – Dermatology, Rutgers Health / Robert Wood Johnson Medical School (2002–2005)
Fellowship/Additional Training – General Dermatology | Advanced Medical and Procedural Dermatology
Subspecialty Focus – General Dermatology | Psoriasis | Contact Dermatitis | Inflammatory Skin Disease | Skin Cancer Screening
Medical Conditions Treated
- Psoriasis and Psoriatic Skin Disease
- Skin Rashes (Lichen Simplex Chronicus, Prurigo, Pruritus)
- Contact Dermatitis (Irritant and Allergic)
- Skin Infections and Cellulitis (Bacterial, Fungal, Viral)
- Skin Disorders (Acne, Rosacea, Vitiligo, Scleroderma, Eczema)
- Atopic Dermatitis (Eczema) and Inflammatory Skin Conditions
- Skin Cancer (Basal Cell Carcinoma, Squamous Cell Carcinoma, Melanoma)
- Actinic Keratosis and Precancerous Skin Lesions
- Warts and Viral Skin Conditions
- Moles, Cysts, and Benign Skin Growths
- Seborrheic Dermatitis and Scalp Conditions
- Rosacea and Facial Redness
- Hair Loss (Alopecia) and Scalp Disorders
- Hyperpigmentation, Melasma, and Sun Damage
- Nail Disorders and Fungal Nail Infections
Medical Procedures Performed
- Comprehensive Skin Evaluation and Full-Body Skin Cancer Screening
- Skin Biopsy (Shave, Punch, and Excisional)
- Cancerous and Precancerous Skin Growth Removal
- Cryosurgery (Liquid Nitrogen Treatment for Lesions and Warts)
- Electrosurgery and Cauterization
- Dermoscopy (Skin Lesion Analysis and Evaluation)
- Patch Testing for Contact Dermatitis and Allergen Identification
- Laser Therapy (Pigmentation, Vascular Conditions, Skin Resurfacing)
- Chemical Peels and Skin Resurfacing
- Phototherapy for Psoriasis and Chronic Inflammatory Skin Conditions
- Cosmetic Filler Injections (Dermal Fillers)
- Botulinum Toxin (Botox) Injections for Wrinkles
- Hair and Tattoo Removal
- Acne Extraction and Intralesional Corticosteroid Injections
- Scar Revision and Treatment
Services Offered
Dr. Lefkowicz’s dermatology practice at Debra J. Wattenberg, M.D., P.C. on the Upper East Side of Manhattan offers a comprehensive and patient-focused range of medical, procedural, and preventive dermatological services — delivered with the attentiveness, clarity, and personalized care that her patients consistently celebrate. Her practice serves the full spectrum of skin health needs for adults in New York City and the surrounding metropolitan area, from routine annual skin exams and common inflammatory skin conditions through complex chronic dermatological disease management and surgical skin cancer care.
Medical dermatology is the broad clinical foundation of Dr. Lefkowicz’s practice. She provides expert evaluation and ongoing management of a wide range of skin conditions — including psoriasis, eczema, contact dermatitis, acne, rosacea, skin infections, and inflammatory rashes — approaching each condition with thorough diagnostic evaluation and individualized treatment planning. Her particular expertise in psoriasis — a chronic, immune-mediated skin condition that significantly impacts quality of life and often requires sophisticated systemic or biologic therapy — reflects her deep engagement with one of dermatology’s most clinically complex and rapidly evolving treatment landscapes. For patients with chronic or recurrent skin conditions, she provides structured long-term management with regular monitoring and therapy adjustments, ensuring that treatment remains effective and well-tolerated over time.
Skin cancer screening and preventive dermatological care represent a critically important service dimension within Dr. Lefkowicz’s practice. New York City’s diverse and aging patient population faces significant skin cancer risk, and Dr. Lefkowicz provides thorough full-body skin examinations and dermoscopic evaluation of suspicious lesions — ensuring early detection of potentially malignant skin changes and prompt surgical management when necessary. Her patients particularly appreciate her ability to explain dermatological findings, biopsy results, and treatment plans in clear, accessible terms — a quality reflected in her perfect patient scores for answering questions and clarity of instructions, and in her Clearly Explains patient award.
Her affiliation with Mount Sinai Hospital — the #1 hospital in New York and a Best Hospitals Honor Roll institution — provides her patients with the assurance that, when more complex dermatological conditions require hospital-level evaluation or multidisciplinary management, they have access to the finest academic medical resources available in the United States.
Services include:
- Comprehensive dermatological evaluations and full-body skin health assessments
- Full-body skin cancer screening and mole mapping
- Psoriasis evaluation, management, and advanced therapy coordination
- Eczema and atopic dermatitis diagnosis and treatment
- Contact dermatitis evaluation and patch testing for allergen identification
- Acne and cystic acne treatment — medical and procedural
- Rosacea evaluation and ongoing management
- Skin infection and cellulitis evaluation and treatment
- Cancerous and precancerous skin growth removal
- Skin biopsy and pathological lesion evaluation
- Cryosurgery for lesions, warts, and precancerous growths
- Phototherapy for psoriasis and chronic skin conditions
- Laser therapy for pigmentation, vascular conditions, and skin resurfacing
- Chemical peels and cosmetic skin resurfacing
- Cosmetic filler and Botox injections for facial rejuvenation
- Hair and tattoo removal
- Scar revision and treatment
- Vitiligo and pigmentation disorder management
Accepted Insurances
- CMS Medicare
- VillageCareMAX (HMO, Medicare)
Please contact the practice directly to confirm additional insurance plans accepted, as coverage may vary.
Practice Locations
Location 1 Debra J. Wattenberg, M.D., P.C.address: 875 Fifth Avenue New York, NY 10065
Phone: (212) 288-3200
Hospital Affiliations
- Mount Sinai Hospital — New York, NY (Best Hospitals Honor Roll | Ranked #1 in New York)

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