Dr. George C. Perdikis

Name: George C. Perdikis

Specialty: Neurosurgery

Subspecialties: General Neurosurgery | Pain

Qualification / Board Certification: MD – University of California, Irvine, School of Medicine; Residency in Neurological Surgery, University of California, Irvine

Affiliation(s): Georgeperdikis (Private Practice)

Location: Lancaster, California

Languages Spoken: English

Accepting New Patients: Yes

NPI Number: 1336178128 (Provider & Practice NPI)

About the Doctor

Dr. George C. Perdikis is a seasoned neurosurgeon with more than two decades of experience in the diagnosis, surgical management, and treatment of complex neurological and spinal conditions. He earned his medical degree from the University of California, Irvine, School of Medicine, and completed his internship in Transitional Year medicine at the prestigious Cedars-Sinai Medical Center from 1985 to 1986. He then went on to complete his residency in Neurological Surgery at the University of California, Irvine from 1986 to 1991 — establishing a strong academic and clinical foundation that has defined his career ever since.

Based in Lancaster, California, Dr. Perdikis operates his own private neurosurgery practice at 1669 W. Ave-J, Suite #308, where he sees patients for a broad range of neurosurgical and pain-related conditions. His subspecialties in General Neurosurgery and Pain management position him as a comprehensive resource for patients dealing with everything from brain and spinal disorders to chronic pain conditions requiring surgical or interventional solutions. Dr. Perdikis has earned notable patient experience recognition, including awards for being a doctor patients recommend and for clearly explaining medical information — a testament to his strong communication style and patient-centered approach.

Dr. Perdikis currently accepts a wide range of insurance plans, including Medicaid and Medicare, making his specialized services accessible to a broad patient population in the Antelope Valley region of California. He is currently accepting new patients.

Highlights at a glance:

• Over 20 years of neurosurgical experience
• Subspecialties in General Neurosurgery and Pain management
• Trained at UC Irvine and Cedars-Sinai Medical Center
• Patient award recipient – “Patients Recommend” and “Clearly Explains”
• Accepts Medicare, Medicaid, Blue Cross Blue Shield, and more
• Active California state medical license through 2026
• Currently accepting new patients

Education & Training

Medical School

• University of California, Irvine, School of Medicine – MD

Internship

• Cedars-Sinai Medical Center – Transitional Year Internship (1985–1986)

Residency

• University of California, Irvine – Residency in Neurological Surgery (1986–1991)

Fellowship / Additional Training

• Subspecialty focus in General Neurosurgery and Pain Management

Medical Conditions Treated

Dr. Perdikis evaluates, manages, and surgically treats a wide spectrum of neurological and spinal conditions, including:

• Brain tumors (benign and malignant)
• Intracranial hemorrhage and brain bleeds
• Head trauma and traumatic brain injury (TBI)
• Spinal cord injuries and spinal trauma
• Herniated discs (cervical, thoracic, and lumbar)
• Spinal stenosis
• Degenerative disc disease
• Sciatica and radiculopathy
• Chronic back and neck pain
• Failed back surgery syndrome
• Hydrocephalus
• Peripheral nerve disorders
• Spinal tumors and lesions
• Carpal tunnel syndrome and nerve entrapments
• Neuralgia and neuropathic pain conditions

Medical Procedures Performed

• Minimally invasive spine surgery
• Craniotomy and brain tumor resection
• Spinal decompression surgery (laminectomy, discectomy)
• Spinal fusion procedures
• Cervical and lumbar disc replacement
• Intracranial pressure monitoring
• Nerve decompression and release surgery
• Vertebroplasty and kyphoplasty
• Pain management procedures and interventions
• Neurodiagnostic imaging review and interpretation (MRI, CT)
• Intraoperative neurological monitoring
• Shunt placement for hydrocephalus
• Peripheral nerve surgery
• Pre- and post-surgical neurological consultations

Services Offered

Dr. Perdikis offers a full range of neurosurgical and pain management services from his Lancaster-based private practice, serving patients across the Antelope Valley and surrounding communities. His approach combines advanced surgical expertise with a strong emphasis on patient education and communication — qualities that have earned him formal recognition from his patients.

His general neurosurgery services cover the full scope of brain and spinal surgery, from the evaluation of acute neurological emergencies to the elective surgical management of chronic conditions that have not responded to conservative treatment. Whether a patient presents with a newly diagnosed brain tumor, a spine injury from an accident, or years of debilitating back pain, Dr. Perdikis provides individualized surgical planning and comprehensive pre- and post-operative care.

His pain management subspecialty adds an important dimension to his practice. Rather than defaulting immediately to surgery, Dr. Perdikis evaluates each patient’s pain condition holistically, considering interventional pain procedures, nerve blocks, and other non-surgical or minimally invasive options before recommending more extensive surgical intervention. This balanced, evidence-based approach ensures patients receive the most appropriate level of care for their specific situation.

Services include:

• Comprehensive neurosurgical consultations and second opinions
• Minimally invasive and open spine surgery
• Brain tumor evaluation and surgical treatment
• Traumatic brain and spinal injury management
• Chronic and acute pain assessment and management
• Diagnostic imaging review (MRI, CT, X-ray)
• Pre-operative planning and surgical preparation
• Post-operative care and rehabilitation coordination
• Nerve entrapment and peripheral nerve surgeries
• Spinal deformity evaluation and correction
• Patient education and individualized treatment planning
• Coordination of care with neurologists, oncologists, and primary care physicians

Accepted Insurances

• Blue Cross Blue Shield of Michigan (PPO)
• Elevance (HMO, PPO, POS, Medicare, Medicaid)
• Medicaid
• Medicare
• Regence Health Plans (PPO)

Please contact the practice directly to verify that your specific plan is accepted before scheduling an appointment.

Practice Location

Location 1 Practice Name: George perdikis (Private Practice)

Address: 1669 W. Ave-J, Suite #308, Lancaster, CA 93534

Phone: (661) 940-5155

Hospital Affiliations

No hospital affiliations are currently listed in available public records. Patients are encouraged to contact the practice directly for information regarding surgical facility affiliations and hospital privileges.

Licensure

Profile information sourced from U.S. News Health and public records. For appointments, insurance verification, or additional inquiries, please contact the practice directly at (661) 940-5155.